ERECTILE DYSFUNCTION IN PATIENTS WITH HAEMOPHILIA

Patients with haemophilia now live nearly normal lives thanks to replacement therapy. As a result, many aging-related health issues are emerging in the haemophilic population. One such problem, rarely discussed, is erectile dysfunction.

Bleeding related with sexual activity is common among men with haemophilia (occurring in 45% of cases), and 40% of them feel that their bleeding disorder has a negative influence on their sex life.

Symptoms of erectile dysfunction appear prevalent in people with haemophilia, particularly among older individuals. Several risk factors for sexual dysfunction are present in the haemophilic population, including a history of bleeding from the iliopsoas muscle (located in the iliac region of the body) during intercourse, the impact of chronic pain and arthropathy on sexual desire and positions, which emotionally scar the intimacy of patients with this chronic disease.

Unfortunately, sexual function has not been well studied in people with haemophilia, although surveys of affected patients show a clear need for information about sexual health issues.

It is, therefore, still difficult to distinguish the relative impact of joint pain, reduced mobility, fear of bleeding, and the effect of certain medications on sexual function in patients with severe haemophilia and haemophilic arthropathy.

 

Reference:

  • Yang M, Sun H(, Jackson SC. Erectile dysfunction in patients with haemophilia. Haemophilia. 2019;00:1–6. https://doi.org/10.1111/hae.13707
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Wikiphilia

Learn more about the meaning of the words you read on this page and learn about the entire glossary on hemophilia.

The amount of minerals present in a square centimetre of bone.

Fuoriuscita di sangue dai vasi sanguigni che si verifica in seguito al danneggiamento delle loro pareti.

L’emorragia si definisce interna nei casi in cui il sangue defluisce in una cavità naturale del corpo, o esterna quando il sangue si riversa all’esterno o in una cavità comunicante con l’esterno.

A protein belonging to the clotting factor category, a group of enzymes involved in the blood-clotting process.

It is encoded by a gene on the long arm of the X chromosome.

Factor VIII is also known as anti-haemophilic factor (AHF).

Product containing a high concentration of freeze-dried factor VIII, used for replacement therapy in the treatment of haemophilia A.

A ereditary genetic illness, characterised by a deficiency of clotting factor VIII, that exposes the individual to a greater risk of both internal and external bleeds.

Haemophilia A is more common in males, whereas females tend to be healthy carriers of the condition.

The typical symptoms of the condition include haemarthroses (joint bleeds) and haematomas (muscle bleeds).

Condition that occurs when factor VIII activity is between 1% and 5%.

Condition that occurs when factor VIII activity is between 1% and 5%.

Condition that occurs when factor VIII activity is <1%.